WebThis biofilm-induced hyperinfectivity may be due in part to a higher growth rate of biofilm-derived cells during infection. These results suggest that the infectious dose of naturally … Web5 dec. 2011 · Challenge of outer-membrane vesicle (OMV)–immunized mice with hyperinfectious, mouse-passaged Vibrio cholerae.A, ID 50 (the dose at which half the animals are infected) for secondary infection using, as inoculae, mouse-passaged V. cholerae E7946 recovered from primary infection small intestinal (SI) homogenates. …
Emergence of a ‘hyperinfectious’ bacterial state after passage of ...
Web6 dec. 2005 · They assumed that the number of hyperinfectious bacteria (i.e., those from fresh feces of a sick patient) necessary to cause disease was smaller than the … WebThe ‘hyperinfectious’ state was found to dramatically reduce the dose required to infect secondary individuals, and also influenced the tissue distribution of colonizing bacteria, … ginn obituary
Vibrio cholerae Released by Protozoa are Hyperinfectious
Web12 apr. 2012 · Hyperinfectious strains are among the most virulent salmonellae reported, were restricted to certain serovars, and vaccination conferred poor protection against … WebThe ‘hyperinfectious’ state is likely to be shared among host-passaged pathogens. Unravelling the molecular basis of this phenotype, by comparing the transcriptomes or proteomes of host-passaged bacteria to laboratory-grown bacteria, would highlight targets that could be used to develop new strategies for controlling the transmission of … Web6 dec. 2005 · Incorporation of this hyperinfectious state into our disease model provides a much better fit with the observed epidemic pattern of cholera. These findings help to substantiate the clinical relevance of laboratory observations regarding the hyperinfectious state, and underscore the critical importance of human-to-human versus environment-to … fullscreen game keyboard shortcut